Tomato juice can kill salmonella, the bacteria that terrorizes our guts: ScienceAlert

Tomato juice can kill salmonella, the bacteria that terrorizes our guts: ScienceAlert

A new study has found that tomatoes can help fight bacterial infections in your gut.

One of the world’s most widely consumed vegetables (or perhaps fruit?), it’s packed with antioxidants, vitamins and other compounds – two of which scientists at Cornell University in the US have identified for their powerful bacteria-killing properties in a series of products. Cell experiments.

The research team, led by Cornell University microbiologist Jeong-Min Song, was interested in this Salmonellaa genus of intestinal bacteria that invade the intestines, often causing food poisoning.

Specifically, the team focused on one serotype of typhoid Salmonella, Salmonella enterica Typhi, which lives only in humans and causes typhoid fever when it slips into the bloodstream from the intestines and spreads through the body.

As with other foodborne pathogens, proper food handling and storage as well as access to antibiotics can help people avoid food poisoning. Salmonella.

However, typhoid fever remains a major public health problem in many parts of the world where people do not have access to clean water, sanitation, or typhoid vaccines. It spreads from person to person through contaminated food and water, and children are most at risk.

In 2016, the world’s first outbreak of drug-resistant typhoid swept through Pakistan, and eight years later, infectious disease experts still fear it could lead to a regional or global outbreak if not controlled.

Malnutrition is also common in Pakistan and other countries throughout Asia, Africa, Latin America and the Caribbean. A 2023 study in 64 countries found that nearly half of children under the age of two had no fruits or vegetables in their diet.

“Our main goal in this study was to find out whether tomatoes and tomato juice could kill enteric pathogens, including… Salmonella “Typhi, and if so, what qualities do they have that make them work,” Song explains.

Cultures grown in the laboratory Salmonella Typhi was killed when exposed to fresh tomato juice within 24 hours, not by the acidity of the juice.

The researchers scanned the tomato genome (Solanum tomato) Search for genes that encode small proteins called peptides that may function as antimicrobial agents.

Among four initial candidates, the team identified two antimicrobial peptides that inhibit bacterial growth Salmonella Typhi, and even killed a strain resistant to ciprofloxacin, the primary antibiotic used to treat typhoid fever.

Finally, the researchers modeled the shape of two key candidate peptides and simulated their interactions with bacterial cell membranes. As the modeling predicted, the two peptides were cleaved Salmonella Typhoid cell membranes in just 45 minutes.

In other experiments, compounds also killed Salmonella Typhimurium, a non-typhoid strain Salmonella Which causes non-fatal food poisoning.

Keeping in mind that these are just cell experiments, the study results are no reason to guzzle tomato juice by the gallon; No one type of food will work its magic on its own.

Instead, the study emphasizes public health messages encouraging people to eat tomatoes as part of a balanced diet that includes plenty of other fruits and vegetables – and provided they are prepared with good food hygiene methods, this may help avoid illness and food poisoning.

But it depends on affordability and access.

The study was published in Spectrum of microbiology.

You may also like...

Leave a Reply

Your email address will not be published. Required fields are marked *