Study: Men who take Viagra may reduce the risk of Alzheimer’s

Study: Men who take Viagra may reduce the risk of Alzheimer’s

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A study suggests that men who take erectile dysfunction medications, such as Viagra, may reduce their risk of developing Alzheimer’s disease.

In research conducted on more than 260,000 men, those who took the drugs were 18% less likely to develop the condition causing dementia.

But more research is needed to prove that medications cause this effect.

But scientists also continue to search for existing medications that can prevent or delay the development of the disease in the first place.

Prescription records

Medications like Viagra were originally designed to treat high blood pressure and angina. They work by acting on a cell signaling messenger that may also be linked to memory.

It is also known to affect brain cell activity, and animal research suggests that it has some protective effect on the brain.

In a new study in Neuroscience, researchers from University College London looked at the prescription records of thousands of men with erectile dysfunction, and compared those who were given the drugs with those who were not.

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Over the next five years, they found 8.1 cases of Alzheimer’s per 10,000 people in the group that was prescribed the drugs, and 9.7 cases in the group that did not take them.

Men who got the most prescriptions for erectile dysfunction medications were less likely to develop Alzheimer’s disease, suggesting that regular use of the drug could have a greater impact on the disease.

The researchers say their study does not show that the drugs themselves were reducing people’s risk of developing Alzheimer’s disease, but it could point to a new avenue of research.

Lead author Dr Ruth Brower said: ‘More research is needed to confirm these findings, learn more about the potential benefits and mechanisms of these drugs and consider the ideal dose.’

The researchers also want to conduct a trial on women and men as well, to see if the drug has any effect.

There are many factors that can cause the disease. The study adjusted its results for some, including age, underlying health conditions, other medications taken and whether the participant was a smoker.

Professor Tara Spiers-Jones, from the University of Edinburgh, and head of the British Neuroscience Centre, said: “This study does not conclusively prove that erectile dysfunction medications reduce the risk of Alzheimer’s disease, but it provides good evidence that this type of medication deserves further study in the future.” . organized.

Dr Francesco Tamanini, a neurophysiologist at the University of Reading, said it was a “great study”, but more solid evidence was needed about how the drug affects the brain.

“It is possible that it has a therapeutic effect directly affecting neurons (if the drug is able to cross the blood-brain barrier) and/or by increasing blood flow, but both of these hypotheses need to be tested,” he said.

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